diff --git a/front_end/ui/legacy/components/utils/TargetDetachedDialog.ts b/front_end/ui/legacy/components/utils/TargetDetachedDialog.ts
index 8b29ae0edb17..9c2b2696009b 100644
--- a/front_end/ui/legacy/components/utils/TargetDetachedDialog.ts
+++ b/front_end/ui/legacy/components/utils/TargetDetachedDialog.ts
@@ -25,7 +25,12 @@ const UIStrings = {
   /**
    *@description Text on the remote debugging window to indicate a disconnection happened because a second dev tools instance was opened
    */
-  websocketDisconnectedNewDebuggerOpened: 'Disconnected due to opening a second DevTools window for the same app.'
+  websocketDisconnectedNewDebuggerOpened: 'Disconnected due to opening a second DevTools window for the same app.',
+  /**
+   *@description Text on the remote debugging window to indicate the React Native instance being debugged was destroyed
+   */
+  websocketDisconnectedPageRemoved:
+      'The React Native instance being debugged no longer exists. Relaunch DevTools to debug a new instance.',
 } as const;
 
 const str_ = i18n.i18n.registerUIStrings('ui/legacy/components/utils/TargetDetachedDialog.ts', UIStrings);
@@ -64,6 +69,10 @@ export class TargetDetachedDialog extends SDK.SDKModel.SDKModel<void> implements
       return i18nString(UIStrings.websocketDisconnectedNewDebuggerOpened);
     }
 
+    if (connectionLostDetails.code === '1000' && connectionLostDetails.reason?.includes('[PAGE_REMOVED]')) {
+      return i18nString(UIStrings.websocketDisconnectedPageRemoved);
+    }
+
     return null;
   }